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telomerase、端粒酶检测、端粒酶相关中美专利技术资料汇编 700M


端粒酶检测、端粒酶相关中国专利


1、00111629.0A 端粒酶活性的定量测定方法 1-15
2、00127583.6A 一种端粒酶活性检测方法 1-9
3、00801875.8A 端粒酶抑制剂及其使用方法 1-224
4、00816440.1A 芳胺衍生物及其作为抗端粒酶剂的用途 1-47
5、01110556.9A 抑制端粒酶活性脱氧核酶寡核苷酸结构及用途 1-10
6、02110521.9A 人端粒酶反转录酶样组分的基因突变体的新用途 1-35
7、02116466.5A 一种检测端粒酶活性的方法 1-18
8、02820847.1A 端粒酶抑制肽及其用途 1-38
9、03139789.1A 抑制白血病细胞端粒酶活性的反义核酸及其应用 1-22
10、200310117343.8A 抑制人端粒酶反转录酶基因表达的siRNA和表达载体及其在制药中的应用 1-32
11、200380107388.5A 检测端粒酶活性的方法和组合物 1-31
12、200410017051.1A 一种人端粒酶活性抑制蛋白及其应用 1-30
13、200410018808.9A 以端粒酶活性判断卵巢上皮性癌药物敏感性的方法 1-7
14、200410040520.1A 抑制端粒酶活性的核酶基因hTERT-5'RZ cDNA、重组载体与核酶 1-10
15、200480009121.7A 使用苏拉明、戊聚糖多聚硫酸酯、端粒酶反义体及端粒酶抑制剂的方法和组合物 1-55
16、200480017246.4A 增加端粒酶活性的组合物和方法 1-69
17、200480025975.4A 用于端粒酶抑制的改性寡核苷酸 1-60
18、200510030526.5A 端粒酶活性抑制蛋白的制备和纯化 1-33
19、200610014236.6A 一种端粒酶活性定量检测方法及试剂盒 1-12
20、200610038270.7A 抑制端粒酶逆转录酶hTERT表达的ShRNA在抗肿瘤中的应用 1-16
21、200610053865.A 聚阳离子脂质体端粒酶反义寡核苷酸复合物及制备 1-13
22、200610115885.5A 端粒酶结合蛋白p23的应用 1-15
23、200680015221.A 端粒酶阳性细胞中端粒长度的调节和癌症治疗 1-29
24、200680052116.3A 用于检测端粒酶活性的测定法 1-85
25、200710027251.9A 携带C57BL 6鼠端粒酶逆转录酶的重组腺病毒载体 1-21
26、200710038640.1A 抗人端粒酶逆转录酶单链抗体 1-13
27、200710068218.0A 人端粒酶基因转导骨髓间充质干细胞的方法 1-29
28、200710078662.0A 一种在端粒酶阳性肿瘤细胞特异表达标记基因和治疗基因的慢病毒及其用途 1-25
29、200710194180.1A 胚胎端粒酶食品 1-3
30、200780001961.2A 鸟类端粒酶反转录酶 1-51
31、200780037882.7A 端粒酶逆转录酶融合蛋白、编码它的核苷酸以及其用途 1-99
32、200810018702.7A 端粒酶抑制剂及其制备方法和用途 1-22
33、200810041324.4A 抑制端粒酶活性的融合蛋白、其制备及应用 1-33
34、200810050478.A 抑制端粒酶活性的金属超分子化合物及用法和用途 1-21
35、200810098490.8A 用于端粒酶抑制的改性寡核苷酸 1-60
36、200810101901.4A 端粒酶永生化人胚胎前脑神经前体细胞系及其建立方法 1-32
37、200880024705.A 端粒酶活化化合物及其使用方法 1-73
38、200880112672.4A 调节端粒酶活性的化合物的鉴定方法 1-67
39、200910188882.8A 一种能激活细胞端粒酶促使肌肤细胞再生修复的技术 1-8
40、200910228532.A 一类用于端粒酶活性检测的引物 1-10
41、200980101271.3A G-quadruplex检测方法、形成G-quadruplex的DNA的检测方法以及端粒酶活性测定方法 1-61
42、200980113118.2A 端粒酶反应的抑制方法 1-29
43、200980149015.1A 端粒酶抑制剂及其使用方法 1-87
44、201010109274.6A 端粒酶永生化的皮肤成纤维细胞系及其构建方法 1-11
45、201010109279.9A 质粒介导的端粒酶RNA基因干扰构建体及其构建方法 1-13
46、201010121477.7A 基于端粒酶显像的肿瘤诊断试剂盒 1-5
47、201010150493.9A 人类的端粒酶催化亚单位 1-259
48、201080023810.9A 用于增加端粒酶活性的组合物和方法 1-74
49、201110101394.6A 双温快循环荧光定量PCR端粒酶活性的检测方法和试剂盒 1-15
50、201110153580.4A 抗端粒酶逆转录酶和人表皮生长因子受体特异性复合IgY及其制备方法 1-35
51、201110182062.5A 一种端粒酶活性的检测方法 1-14
52、201110184601.9A 一种抑制端粒酶活性的肽及其制备方法和应用 1-24
53、201110186565.A 鸟类端粒酶反转录酶 1-37
54、201110326882.7A 一种利用石英晶体微天平筛选端粒酶抑制剂的方法 1-13
55、201110357993.4A 植物端粒酶活性的检测方法 1-10
56、201210190716.3A 一种快速检测端粒酶活性的试剂盒及其应用 1-11
57、95194952.7A 哺乳动物端粒酶 1-73
58、95196101.2A 端粒酶的RNA成分 1-65
59、96198617.4A 检测端粒酶活性的方法 1-33
60、97180256.4A 人类的端粒酶催化亚单位 1-394
61、97199534.6A 端粒酶逆转录酶 1-289
62、98111646.9A 测定端粒酶活性的端粒重复扩增-微孔板杂交法 1-6
63、98124461.0A 抑制端粒酶活性反义寡核苷酸结构及用途 1-10
64、98126955.9A 端粒酶抑制剂 1-17
65、98808383.3A 脊椎动物端粒酶基因和蛋白质及其用途 1-127
66、99809954.6A 来自端粒酶的抗原性肽 1-38

telomerase、端粒酶检测、端粒酶相关美国专利

67、US20010007902 RNASE L ACTIVATORS AND ANTISENSE OLIGONUCLEOTIDES EFFECTIVE TO TREAT 1-37
68、US20010034439 MAMMALIAN TELOMERASE 1-31
69、US20020025518 METHOD FOR THE DETECTION OF TELOMERASE ACTIVITY 1-29
70、US20020028496 Method for producing telomerase reverse transcriptase 1-25
71、US20020102686 Inactive variants of the human telomerase catalytic subunit 1-21
72、US20020107258 Inhibition of human telomerase by a G-quadruplex-interaction compound 1-32
73、US20020120144 Telomerase inhibitors and methods of their use 1-36
74、US20020127634 THERAPY AND DIAGNOSIS OF CONDITIONS RELATED TO TELOMERE LENGTH AND OR 1-86
75、US20020160983 Substituted benzopyranones as telomerase inhibitors 1-40
76、US20020164786 Novel telomerase 1-118
77、US20020173476 Antisense compositions for detecting and inhibiting telomerase reverse 1-34
78、US20020187471 Novel telomerase 1-94
79、US20020193289 Methods and compositions for modulating telomerase reverse transcriptase 1-18
80、US20030009019 NOVEL TELOMERASE 1-214
81、US20030022878 TELOMERASE INHIBITOR 1-12
82、US20030032075 Novel telomerase 1-224
83、US20030040525 Inhibition of human telomerase by a G-quadruplex-interaction compound 1-33
84、US20030044953 Novel telomerase 1-229
85、US20030050264 Methods and compositions for modulating telomerase reverse transcriptase 1-32
86、US20030059787 Novel telomerase 1-230
87、US20030082812 Telomerase immortalized human neural stem cells and 1-26
88、US20030096344 Human telomerase catalytic subunit diagnostic and therapeutic methods 1-103
89、US20030096732 Telomerase expression repressor proteins and methods of using the same 1-49
90、US20030099616 Dual specificity tumor killing vectors driven by the telomerase promoter 1-25
91、US20030100093 Human telomerase catalytic subunit diagnostic and therapeutic methods 1-249
92、US20030104420 Methods and compositions for modulating telomerase reverse transcriptase 1-24
93、US20030105130 Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as 1-67
94、US20030113760 Methods and compositions for use in selectively producing a protein in 1-16
95、US20030134275 Telomerase reverse transcriptase (TERT) genes 1-125
96、US20030143228 Human telomerase reverse transcriptase as a class-II restricted 1-80
97、US20030153076 Mammalian telomerase 1-47
98、US20030162200 Methods for modulating telomerase activity 1-22
99、US20030166660 Combinations comprising N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]- 1-8
100、US20030171326 Methods and compositions for modulating telomerase reverse transcriptase 1-24
101、US20030175766 Therapy and diagnosis of conditions related to telomere length and or 1-69
102、US20030186282 Using purified telomerase to identify telomerase activators and inhibitors 1-22
103、US20030186978 Novel telomerase inhibitors 1-13
104、US20030190638 Methods of screening for compounds that derepress or increase telomerase 1-108
105、US20030204069 Segments of the human gene for telomerase reverse transcriptase 1-211
106、US20030207404 Detection reagents for TPC2 and TPC3, two proteins that are coexpressed 1-62
107、US20030211965 Methods and compositions for modulating telomerase reverse transcriptase 1-16
108、US20030225027 Telomerase reverse transcriptase fragments and uses thereof 1-38
109、US20040009993 Pyridopyrimidinones derivatives as telomerase inhibitors 1-67
110、US20040034023 Use of polycyclic aromatic compounds for making medicines capable of 1-14
111、US20040063665 Substituted benzopyranones as telomerase inhibitors 1-40
112、US20040072787 Telomerase reverse transcriptase transcriptional regulatory sequences and 1-66
113、US20040086518 Universal vaccine and method for treating cancer employing telomerase 1-28
114、US20040102413 Method and reagent for the inhibition of telomerase enzyme 1-85
115、US20040106128 Cancer vaccines containing xenogeneic epitopes of telomerase reverse 1-55
116、US20040132807 Aurones as telomerase inhibitors 1-28
117、US20040142357 Novel telomerase inhibitors and uses therefor 1-74
118、US20040198659 Therapy and diagnosis of conditions related to telomere length and or 1-86
119、US20040219667 Monoclonal antibody for human telomerase catalytic subunit 1-35
120、US20040242529 Vector encoding inactivated telomerase for treating cancer 1-223
121、US20040247613 Treating cancer using a telomerase vaccine 1-225
122、US20040253701 Protein and peptide fragments from mouse telomerase reverse transcriptase 1-117
123、US20050003404 Telomerase interference 1-26
124、US20050009177 Telomerase interference 1-34
125、US20050013825 Vaccine containing the catalytic subunit of telomerase for treating cancer 1-225
126、US20050032094 Regulatory DNA sequences of the human catalytic telomerase sub-unit gene, 1-113
127、US20050037990 Disubstituted 7,9-guanines halides as telomerase inhibitors 1-9
128、US20050059622 Methods and compositions for modulating telomerase reverse transcriptase 1-31
129、US20050070492 Treating cancer using antisense oligonucleotides against telomerase 1-36
130、US20050079608 Lineage committed stem cells selected for telomerase promoter activity 1-25
131、US20050089883 Producing telomerase activators and inhibitors by screening with purified 1-24
132、US20050113325 Modified oligonucleotides for telomerase inhibition 1-36
133、US20050118149 Methods and compositions for modulating telomerase reverse transcriptase 1-31
134、US20050123521 Immortalization of human cells by the ectopic expression of human 1-32
135、US20050153916 RNA interference mediated inhibition of telomerase gene expression using 1-304
136、US20050176022 Vertebrate telomerase genes and proteins and uses thereof 1-96
137、US20050176629 Telomerase expression repressor proteins and methods of using the same 1-42
138、US20050250186 Methods and compositions for modulating telomerase reverse transcriptase 1-16
139、US20050282893 Methods and compositions for using suramin, pentosan, polysulfate, 1-28
140、US20060040307 uman telomerase catalytic subunit 1-226
141、US20060106196 ntigenic peptides derived from telomerase 1-51
142、US20060111365 ombinations comprising N- {5-[4- [4-methy L-piperazino-methyl) 1-8
143、US20060166254 rotocol for optimizing purification of enzymatically active human 1-25
144、US20060166864 ethods for modulating telomerase activity 1-30
145、US20060172960 herapy and diagnosis of conditions related to telomere length and or 1-86
146、US20060204483 ellular telomerase vaccine and its use for treating cancer 1-10
147、US20060204956 ethod for detection of hTR and hTERT telomerase-associated RNA in plasma 1-8
148、US20060239974 nhancing cell migration by increasing telomerase activity 1-51
149、US20060246441 ethods and compositions for detecting telomerase activity 1-19
150、US20060275267 ucleic acids encoding inactive variants of human telomerase 1-22
151、US20060281106 elomerase promoter sequences for screening telomerase modulators 1-52
152、US20070010476 herapy and diagnosis of conditions related to telomere length and or 1-84
153、US20070042962 eptide dependent upregulation of telomerase expression 1-34
154、US20070048294 ETHOD FOR INHIBITING TELOMERASE ACTIVITY 1-25
155、US20070105796 ethod for inhibiting telomerase activity and inhibitor thereof 1-38
156、US20070117773 elomerase-inhibiting ENA oligonucleotide 1-34
157、US20070122401 ethods and compositions for modulating telomerase reverse transcriptase 1-13
158、US20070190561 egments of the Human Gene for Telomerase Reverse Transcriptase 1-204
159、US20070238639 elomerase expression repressor proteins and methods of using the same 1-68
160、US20070282456 ompositions and Methods for Myogenesis of Fat-Derived Stem Cells 1-17
161、US20080004355 ethod for Inhibiting Telomerase Activity and an Agent for Inhibiting the 1-45
162、US20080058277 ethods and compositions for modulating telomerase reverse transcriptase 1-31
163、US20080090778 elomerase reverse transcriptase fusion protein, nucleotides encoding it, 1-74
164、US20080113925 ompositions and Methods for Increasing Telomerase Activity 1-31
165、US20080131442 gY antibodies to human telomerase reverse transcriptase 1-16
166、US20080176223 ethods and compositions for modulating telomerase reverse transcriptase 1-22
167、US20080213812 ethods and compositions for modulating telomerase reverse transcriptase 1-47
168、US20080220438 elomerase Promoter Sequences for Screening Telomerase Modulators 1-49
169、US20080268467 ethods and compositions for modulating telomerase reverse transcriptase 1-12
170、US20090023677 odulation of Telomere Length in Telomerase Positive Cells and Cancer 1-13
171、US20090047672 elomerase RNA Subunit and Methods of Use Thereof 1-52
172、US20090074741 omposition and method for inducing and enhancing a telomerase reverse 1-28
173、US20090111157 rotein and peptide fragments from mouse telomerase reverse transcriptase 1-115
174、US20090142408 elomerase delivery by biodegradable Nanoparticle 1-17
175、US20090142770 air Follicle Pharmacodynamic Assay for Telomerase Activity 1-34
176、US20090143451 OMPOUNDS THAT INCREASE TELOMERASE REVERSE TRANSCRIPTASE (TERT) EXPRESSION 1-15
177、US20090149408 NA INTERFERENCE MEDIATED INHIBITION OF TELOMERASE GENE EXPRESSION USING 1-301
178、US20090202499 uman Telomerase Reverse Transcriptase Peptides 1-49
179、US20090202503 EQUENCE OF NUCLEOTIDES AND PEPTIDES GSE 24.2 OF DYSKERIN, WHICH CAN 1-30
180、US20090226907 SSAY FOR DETECTION OF TELOMERASE ACTIVITY 1-39
181、US20090239219 ELOMERASE EXPRESSION REPRESSOR PROTEINS AND METHODS OF USING THE SAME 1-40
182、US20090253709 YNTHESIS, TELOMERASE INHIBITION AND CYTOTOXIC STUDIES ON 1-27
183、US20090269739 it for detection of telomerase reverse transcriptase nucleic acids 1-211
184、US20090286853 ODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION 1-39
185、US20100003229 uclear telomerase reverse transcriptase variant 1-29
186、US20100010064 ancer treatment by combined inhibition of proteasome and telomerase 1-24
187、US20100016407 ombined Telomerase Inhibitor and Gemcitabine for the Treatment of Cancer 1-18
188、US20100068186 igh affinity telomerase t cell receptors 1-88
189、US20100104586 reatment of Carcinomas with a Combination of EGF-Pathway and Telomerase 1-22
190、US20100158798 P-Pocket-Binding Effectors and Methods for Using the Same to Modulate 1-48
191、US20100160260 RBD-Binding Effectors and Methods for Using the Same to Modulate 1-22
192、US20100173306 ETHOD FOR DETECTING G-QUADRUPLEX, METHOD FOR DETECTING 1-54
193、US20100173378 VIAN TELOMERASE REVERSE TRANSCIPTASE 1-39
194、US20100216150 ethod for Identifying a Compound That Modulates Telomerase Activity 1-55
195、US20100227832 odulation of telomere length in telomerase positive cells and cancer 1-13
196、US20100247657 ELOMERASE REVERSE TRANSCRIPTASE VARIANT 1-45
197、US20100248280 ethod for Identifying a Compound that Modulates Telomerase Activity 1-48
198、US20100260670 LTERNATIVE SPLICE VARIANT PATTERNS OF HUMAN TELOMERASE REVERSE 1-28
199、US20100261162 ethods of assaying for telomerase activity and compositions related to 1-42
200、US20100261246 ETHOD FOR INHIBITING TELOMERASE REACTION 1-30
201、US20100267667 ELOMERASE ACTIVATING COMPOUNDS AND METHODS OF USE THEREOF 1-46
202、US20100292197 ompositions and Methods for Increasing Telomerase Activity 1-54
203、US20110071095 ompositions and Methods for Increasing Telomerase Activity 1-32
204、US20110212454 ssay for Telomerase Activity 1-24
205、US20110257251 ELOMERASE INHIBITORS AND METHODS OF USE THEREOF 1-64
206、US20110263685 ethod for Identification of Sensitivity of a Patient to Telomerase 1-23
207、US20110318832 uman Telomerase Catalytic Subunit 1-216
208、US20120070842 ssay for Telomerase Activity Using Microfluidic Device 1-19
209、US20120094282 ETHOD FOR DETECTING G-QUADRUPLEX, METHOD FOR DETECTING 1-54
210、US20120107863 ODULATION OF TELOMERE LENGTH IN TELOMERASE POSITIVE CELLS AND CANCER 1-14
211、US20120129918 ODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION 1-39
212、US20120309759 creening Method and Compounds for Modulating Telomerase Activity 1-68
213、US20120329858 ODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION 1-38

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